KDIGO classification of AKI (acute kidney injury)
KDIGO (Kidney Disease: Improvement Global Initiative) definition of AKI is characterised by any of the following criteria:
Increase S. Creatinine ≥ 0.3 mg/dl within 48 hrs, or
Increase S. Creatinine ≥ 1.5 times the baseline within last 7 days, or
Urine volume < 0.5 ml/kg/hr for 6 hrs
Severity of the disease is staged according to the following criteria:
Stage 1:
S. creatinine 1.5 - 1.9 times the baseline or Increase > 0.3 mg/dl
Urine output < 0.5 ml/kg/hr for 6 - 12 hrs
Stage 2:
S. creatinine 2.0 - 2.9 times the baseline
Urine output < 0.5 ml/kg/hr for > 12 hrs
Stage 3:
S. creatinine 3.0 times the baseline or Increase > 4.0 mg/dl
eGFR < 35 ml/min
Urine output < 0.3 ml/kg/hr for > 24 hrs
Initiation of renal replacement therapy
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